Main Article Content

Windi Astuti
Moh. Rasyid Kuna
Nanda Sayyida Begum
Nur Wahyu Nadila Ginoga
Muhammad Anugrah Sugeha

Abstract

Hypertension, also known as high blood pressure, is a disease characterized by an increase in systolic blood pressure exceeding 140 mmHg and diastolic blood pressure exceeding 90 mmHg, in several measurements with a time of five minutes and with sufficient rest.  The purpose of this study is to determine the cost effectiveness of hypertension therapy by using a comparison of amlodipine and captopril drug therapy in health service facilities. The method chosen was a literature study taken from journals and the results of previous research from various references related to the cost-effectiveness of antihypertensive therapy. Based on several journal literature or scientific publications that have been researched regarding the cost-effectiveness of amlodipine antihypertensive therapy compared to captopril, the results show that amlodipine has a higher effectiveness compared to captopril based on ACER and ICER values from several previous studies. Based on 10 literatures that have been analyzed, 7 literatures state that amlodipine antihypertensive is more Cost-Effective compared to captopril antihypertensive.

Article Details

How to Cite
Astuti, W. ., Kuna, M. R. ., Begum, N. S. ., Nadila Ginoga, N. W. ., & Sugeha, M. A. . (2025). Article review: Cost effectiveness analysis of antihypertensive amlodipine compared to captopril in health care facilities. Journal of Midwifery and Nursing, 7(2), 278-284. https://doi.org/10.35335/jmn.v7i2.6095
References
Abdulah, R., Siregar, R. F., & Alfian, S. D. (2017). Cost-effectiveness Analysis of Antipsychotic Combination Therapy in Schizophrenia Inpatients. Indonesian Journal of Clinical Pharmacy, 6(1), 61–66. https://doi.org/10.15416/ijcp.2017.6.1.61
Alifiar, I., Idacahyati Program Studi, K. S., & Sekolah Tinggi Ilmu Kesehatan Bakti Tunas Husada, F. (2018). Kajian Farmakoekonomi Penggunaan Obat Antihipertensi pada Pasien Hipertensi yang Dirawat di RSUD Kota Tasikmalaya. Jurnal Pharmascience, 05(02), 126–133. http://jps.unlam.ac.id/
Amir & Kuna. (2024). Analisis Problem Kompatibilitas Pemberian Terapi obat Secara Intravena Terhadap Pengetahuan Dan Praktik Tenaga Kesehatan Di salah satu Rumah Sakit Kotamobagu Analysis of Compatibility Problems of Intravenous Drug Therapy Administration with the Knowledge and Practice of Health Workers in a Hospital at Kotamobagu. In Jurnal Farmasi Tinctura (Vol. 6, Issue 1).
Andayani. (2020). Cost Analysis Of Antidiabetic Drugs For Diabetes Mellitus Outpatient In Kodya Yogyakarta Hospital. In Malaysian Journal of Pharmaceutical Sciences (Vol. 5, Issue 1).
Anjani. (2019). Analisis Efektivitas Biaya (Cost-Effectiveness) Antihipertensi Pada Pasien Hipertensi Komplikasi Diabetes Melitus Tipe 2 Rawat Inap Di RSUD Dr. Moewardi Tahun 2017.
Arief & George. (2020). Pathophysiology of Critical Ill Patients: Focus on Critical Oxygen Delivery.
Baharuddin. (2013). Perbandingan Efektivitas Dan Efek Samping Obat Antihipertensi Terhadap Penurunan Tekanan Darah Pasien Hipertensi Di Puskesmas Baranti Kabupaten Sidenreng Rappang. Comparation Between Effectiveness And Side Effect Of Antihypertension On Decreasing Blood Pressure Of Hypertension Patients In Baranti Health Centre Of Sidenreng Rappang Regency. 1–43.
Bulan. (2020). Analisis Efektivitas Biaya Obat Captopril Dan Amlodipin Pada Pasien Hipertensi Dengan Penyakit Penyerta Diabetes Mellitus Di Puskesmas Kabupaten Magelang Laporan Hasil Tugas Akhir.
Bulan, M. I., Annisaa, E., & Dini, I. R. E. (2022). Cost Effectiveness Analysis of Captopril And Amlodipine in Hypertensive Patients with Diabetes Mellitus at Magelang Regency Health Center. DIPONEGORO MEDICAL JOURNAL (Jurnal Kedokteran Diponegoro), 11(5), 237–241. https://doi.org/10.14710/dmj.v11i5.35368
Dianati, S., Prasetyawan, F., Rahmawati, N., Widi Astutik, W., Selomangleng No, J., Kediri, K., & Timur, J. (2023). Analisis Efektivitas Biaya Antihipertensi Oral Candesartan Dan Amlodipin Pada Pasien Hipertensi Rawat Inap Rs Bhayangkara Kediri. In || Jilid (Vol. 9).
Hadning et al. (2019). COST EFFECTIVENESS ANALYSIS USE OF CAPTOPRIL AND AMLODIPIN IN PATIENT PRIMARY HYPERTENSION PATIENTS IN SEYEGAN HEALTH CENTER.
Hasan, R., Rasyid Kuna, M., & Ismail, S. A. (2023). Jambura Journal Of Health Science And Research Analisis Bahan Kimia Obat Dalam Jamu Pegal Linu Menggunakan Metode Kromatografi Gas-Spektrometri Massa Chemical Drug Analysis In Joint-Pain Herbal Medicine Using Liquid Chromatography-Mass Spectrometry Method. https://ejurnal.ung.ac.id/index.php/jjhsr/index
Irganda. (2021). Skripsi Analisis Efektivitas Biaya Terapi Antihipertensi Pada Pasien Hipertensi Dengan Penyakit Penyerta Diabetes Melitus Tipe 2 Rawat Inap Di Rsud Pandang Arang Boyolali.
Kristanti. (2015). Efektifitas Dan Efek Samping Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Di Puskesmas Kalirungkut Surabaya. Calyptra: Jurnal Ilmiah Mahasiswa Universitas Surabaya, 4(2).
Kuna, M. R., Widodo, G. P., & Rahmawati, I. (2023). Identifikasi potensi drug related problems diabetes melitus tipe 2 dengan penyakit komorbid pasien rawat jalan. MEDIA ILMU KESEHATAN, 12(1), 102–115. https://doi.org/10.30989/mik.v12i1.849
Makalalag & Rasyid. (2024). Pengaruh Curcuma zedoaria Rosc. Terhadap Kadar ALT dan AST Tikus (Rattus norvegicus) di Induksi DMBA dan Sinar UV B. In Jurnal Ilmiah Farmasi (Vol. 2, Issue 2).
Mappa & Kuna. (2022). Pengaruh Health Education terhadap Penggunaan Imunomodulator Herbal sebagai Pencegahan COVID-19. Wiraraja Medika?: Jurnal Kesehatan, 12(2).
Mokodompit et al. (2025). Sosialisasi Tentang Pencegahan Stunting Di Desa Padang Barat Kecamatan Bintauna. Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN), 6(2), 3466–3471. https://doi.org/DOI:http://doi.org/10.55338/jpkmn.v6i2.5401
Nilansari et al. (2020). Gambaran Pola Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD Panembahan Senopati. Jurnal Ilmu Kefarmasian, 1(2).
Normansyah. (2020). PERBANDINGAN EFEKTIFITAS BIAYA PENGOBATAN AMLODIPIN DENGAN CAPTOPRIL PADA PASIEN HIPERTENSI RAWAT JALAN DI PUSKESMAS KECAMATAN JOHAR BARU PADA TAHUN 2018.
Tabita. (2022). ANALISIS EFEKTIVITAS BIAYA TERAPI PADA PASIEN HIPERTENSI RAWAT JALAN DENGAN TERAPI AMLODIPINEDAN CAPTOPRIL DI KLINIK MERAH PUTIH UNGARAN PERIODDE NOVEMBER 2022.
Tantri. (2020). Analisis Efektivitas Biaya Pengobatan Skizofrenia Menggunakan Clozapine dan Risperidone di Rumah Sakit Jiwa Daerah Sungai Bangkong Periode Januari-Desember. www.stikes-khkediri.ac.id
Tyas et al. (2021). ANALISIS EFEKTIVITAS BIAYA TERAPI ANTIHIPERTENSI PADA PASIEN HIPERTENSI DENGAN PENYAKIT PENYERTA DIABETES MELITUS TIPE 2 RAWAT INAP DI RSUD KOTA MADIUN. In Duta Pharma Journal (Vol. 1, Issue 1).
Wirawan. (2020). Wayan Wirawan. JFERMAKU, 5(1), 1–6. http://ojs.stikes-muhammadiyahku.ac.id/index.php/jfarmaku
Winta et al. (2018). Hubungan kadar gula darah dengan tekanan darah pada lansia penderita Diabetes Tipe 2. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery), 5(2), 163–171. https://doi.org/10.26699/jnk.v5i2.art.p163-171