Overview of Triglyceride levels in Lipemic Serum using Polyethylene Glycol (PEG) 6000
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Published:
Sep 28, 2023
Keywords:
Interference, Lipemic Serum, Polyethylene Glycol (PEG) 6000, Triglyceride Levels
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Abstract
Lipemic causes interference with wavelength and light scattering caused by the presence of lipid particles. This study aims to determine the description of triglyceride levels in lipemic serum with and without the addition of polyethylene glycol (PEG) 6000. This type of research is experimental. The research conducted was descriptive research. The samples used were lipemic serum totaling 30 samples with triglyceride levels above 300 mg/dl. The results of the data analysis showed a mild lipemic level of 22 samples with an average of 379.00 mg/dl, a moderate lipemic level of 5 samples with an average of 558.40 mg/dl, and a severe lipemic serum of 3 samples with an average of 943.40 mg/dl. Based on the results of triglyceride levels without the addition of PEG 6000, the average level is 465.33 mg/dl, while the results of triglyceride levels using PEG 6000, the average level is 243.23 mg/dl. Based on the difference in triglyceride levels before and after adding PEG 6000, namely at the mild level, the average is 215.00 mg/dl (56%), at the moderate level, the average is 261.00 mg/dl (46%), and at the severe level, the average is 212.30 mg/dl (22%). It can be concluded that there are differences in triglyceride levels in lipemic serum before and after adding PEG 6000.
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Sugiah, S., Budiarti, K. D. ., Nurisani, A. ., Mutmaina , G. N. ., & NSY, A. . (2023). Overview of Triglyceride levels in Lipemic Serum using Polyethylene Glycol (PEG) 6000. Journal of Midwifery and Nursing, 5(3), 119-125. https://doi.org/10.35335/jmn.v5i3.4187
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Yousaf, A. M., Malik, U. R., Shahzad, Y., Mahmood, T., & Hussain, T. (2019). Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: preparation and in vitro characterization. Journal of Pharmaceutical Analysis, 9(1), 34–39.
Arooj, A., Farooq, M. S., Umer, T., & Shan, R. U. (2022). Cognitive internet of vehicles and disaster management: a proposed architecture and future direction. Transactions on Emerging Telecommunications Technologies, 33(8), e3625.
Aryani, T. (2021). Evaluasi Pengolahan Serum Lipemik terhadap Pemeriksaan Kadar Kolesterol Total dan Trigliserida. Anakes: Jurnal Ilmiah Analis Kesehatan, 7(2), 110–122.
Chakravarthy, P. S. A., Grandhi, S., Swami, R., & Singh, I. (2023). Quality by design based optimization and development of cyclodextrin inclusion complexes of quercetin for solubility enhancement. Biointerface Res Appl Chem, 13(5), 424.
Chougule, A., Jagtap, V., Nikam, A., Kale, S., Nambiar, K., Bagayatkar, P., Chandrani, P., Kaushal, R., Noronha, V., & Patil, V. (2022). Comprehensive development and implementation of good laboratory practice for NGS based targeted panel on solid tumor FFPE tissues in diagnostics. Diagnostics, 12(5), 1291.
Ii, B., Pustaka, T., & Pustaka, A. T. (2016). Poltekkes Kemenkes Yogyakarta. 1–235.
Lans, W., & Van der Voordt, D. J. M. (2002). Descriptive research. In Ways to study and research urban, architectural and technical design (pp. 53–60). DUP Science.
Lenicek Krleza, J., Honovic, L., Vlasic Tanaskovic, J., Podolar, S., Rimac, V., & Jokic, A. (2019). Post-analytical laboratory work: national recommendations from the Working Group for Post-analytics on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Biochemia Medica, 29(2), 228–261.
Li, W.-J., Chen, H., Tong, M.-L., Niu, J.-J., Zhu, X.-Z., & Lin, L.-R. (2022). Comparison of the yield and purity of plasma exosomes extracted by ultracentrifugation, precipitation, and membrane-based approaches. Open Chemistry, 20(1), 182–191.
Lysaght, T., Lim, H. Y., Xafis, V., & Ngiam, K. Y. (2019). AI-assisted decision-making in healthcare: the application of an ethics framework for big data in health and research. Asian Bioethics Review, 11, 299–314.
Mahon, C. R., & Lehman, D. C. (2022). Textbook of diagnostic microbiology-e-book. Elsevier Health Sciences.
McPherson, R. A., & Pincus, M. R. (2021). Henry’s clinical diagnosis and management by laboratory methods E-book. Elsevier Health Sciences.
Mimi Sugiarti, E. S. (2021). Pengaruh Poliethilen Glikol 6000 8 % pada Serum Lipemik terhadap Hasil Effect of Polyethylene Glycol 6000 . 8 % in Lipemic Serum on Glucose Examination Results SGOT and SGPT. Jurnal Analis Kesehatan, 10(1), 56–61.
Permatasari, I. (2015). Gambaran Kadar Trigliserida pada Serum Lipemik. Journal of Geotechnical and Geoenvironmental Engineering ASCE, 120(11), 259.
Petersen, L. M., Martin, I. W., Moschetti, W. E., Kershaw, C. M., & Tsongalis, G. J. (2019). Third-generation sequencing in the clinical laboratory: exploring the advantages and challenges of nanopore sequencing. Journal of Clinical Microbiology, 58(1), e01315-19.
Sari, W. M., Hardisari, N. R., & Sujono. (2017). Perbedaan Kadar Kreatinin Pada Serum Lipemik Yang Diolah Dengan Polyethylene Glycol High Speed 6000 8% Dan Sentrifugasi. Jurnal Teknologi Kesehatan, 13(1), 45–49.
Schwingshackl, L., & Hoffmann, G. (2013). Comparison of effects of long-term low-fat vs high-fat diets on blood lipid levels in overweight or obese patients: a systematic review and meta-analysis. Journal of the Academy of Nutrition and Dietetics, 113(12), 1640–1661.
Siedlecki, S. L. (2020). Understanding descriptive research designs and methods. Clinical Nurse Specialist, 34(1), 8–12.
Spaggiari, D., Desfontaine, V., Cruchon, S., Guinchard, S., Vocat, A., Blattes, E., Pitteloud, J., Ciullini, L., Bardinet, C., & Ivanyuk, A. (2019). Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma. PloS One, 14(5), e0217139.
Styawan, I. M. (2021). Gambaran Kadar Trigliserida Darah Pada Perokok Aktif. Nuevos Sistemas de Comunicación e Información, 1(13–17), 2013–2015.
Susilawati. (2023). REMAJA DAN MASALAH KESEHATAN.
Watuseke, A. E., Polii, H., & Wowor, P. M. (2016). Gambaran kadar lipid trigliserida pada pasien usia produktif di Puskesmas Bahu Kecamatan Malalayang Kota Manado periode November 2014 –Desember 2014. EBiomedik, 4(2).
Yang, Z., Xiao, D., Ling, K. H. J., Tarnowski, T., Humeniuk, R., Parmentier, B., Fu, Y.-H. A., Johnson, E., Luna, M. L., & Goudarzi, H. (2022). The determination of Sulfobutylether ?-Cyclodextrin Sodium (SBECD) by LC-MS/MS and its application in remdesivir pharmacokinetics study for pediatric patients. Journal of Pharmaceutical and Biomedical Analysis, 212, 114646.
Yousaf, A. M., Malik, U. R., Shahzad, Y., Mahmood, T., & Hussain, T. (2019). Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: preparation and in vitro characterization. Journal of Pharmaceutical Analysis, 9(1), 34–39.
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