Literature study: Activity of white turmeric (Curcuma zedoaria) as an anti-inflammatory
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Published:
Aug 30, 2023
Keywords:
Activity, Anti-Inflammatory, Curcuma Zedoaria
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Abstract
Inflammation is a response given by the body to protect the body against cellular damage, characterized by swelling, redness accompanied by a sensation of heat and pain. Long term use of NSAIDs (Non Steroid Anti Inflammatory Drugs) has side effects such as ulcers, stomach upset, bleeding, nausea, disturbances in the kidneys and the cardiovascular system. White turmeric (Curcuma zedoaria) is a plant that can be used as an anti-inflammatory. This study aims to determine the anti-inflammatory activity of White Turmeric (Curcuma zedoaria) through a literature review in the form of national and international articles or journals. The results of a study of 8 articles that met the inclusion requirements showed that White Turmeric has anti-inflammatory activity. The content of curcumin, essential oils and flavonoids in white turmeric has similarities with NSAIDs, namely by inhibiting the formation of inflammatory mediators.
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How to Cite
Udayani, N. N. W., Sari, N. N. A. P. ., Putra, I. M. A. S. ., Suwantara, I. P. T. ., Sasadara, M. M. V. ., & Adnyani, N. P. L. . (2023). Literature study: Activity of white turmeric (Curcuma zedoaria) as an anti-inflammatory. Journal of Midwifery and Nursing, 5(3), 68-74. https://doi.org/10.35335/jmn.v5i3.4092
References
Arulselvan, P., et. a. (2016). Role of Antioxidants and Natural Products in Inflammation’. Oxidative Medicine and Cellular Longevity.
Ayati, Z., Ramezani, M., Amiri, M. S., Moghadam, A. T., Rahimi, H., Abdollahzade, A., Sahebkar, A., & Emami, S. A. (2019). Ethnobotany, Phytochemistry and Traditional Uses of Curcuma spp. and Pharmacological Profile of Two Important Species (C. longa and C. zedoaria): A Review. Current Pharmaceutical Design, 25(8), 871–935. https://doi.org/10.2174/1381612825666190402163940
Gozali, K., Erny, T., Fiska, W. M., & Rico, S. A. (2022). Acute Toxicity of Extract of White Turmeric Rhizome (Curcuma Zedoaria) Review of Ld50 and Blood Cell Components. Jambura Journal of Health Sciences and Research, 4(3), 648–655. https://doi.org/10.35971/jjhsr.v4i3.13309
He, Y., et. a. (2015). Curcumin, inflammation, and chronic diseases: How are they linked? Molecules, 20(5), 9183–9213.
Hussain, T., et al. (2016). Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?’,. Oxidative Medicine and Cellular Longevity.
Jeong Ha, S., Song, K. M., Lee, J., Ho Kim, Y., Hyouck Lee, N., Eon Kim, Y., Lee, S., & Keun Jung, S. (2018). Preventive effect of Curcuma zedoaria extract on UVB-induced skin inflammation and photoaging. Journal of Food Biochemistry, 42(5), 1–11. https://doi.org/10.1111/jfbc.12598
Kim, K. M., Lee, J. Y., Jeon, B. H., Quan, K. T., Na, M., Nam, K. W., & Chae, S. (2021). Extract of curcuma zedoaria r. Prevents atherosclerosis in apolipoprotein e-deficient mice. Nutrition Research and Practice, 15(3), 319–328. https://doi.org/10.4162/nrp.2021.15.3.319
Lo, jia ye, Kamarudin, muhamad noor alfarizal, Hamdi, omer abdalla ahmed, Awang, K., & Kadir, habsah abdul. (2015). Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-?B activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells. https://doi.org/10.1039/c5fo00607d
Meltyza, E., et al. (2015). Perbandingan efek antiinflamasi ekstrak etanol kunyit putih (Curcuma zedoaria) dengan natrium diklorofenak pada tikus yang diinduksi dengan carrragenan’. Prosiding Pendidikan Dokter, 112–118.
Meltyza, E., Indriyanti, R. A., & Rahimah, S. B. (2015). Perbandingan efek antiinflamasi ekstrak etanol kunyit putih (Curcuma zedoaria) dengan natrium diklorofenak pada tikus yang diinduksi dengan carrragenan. Prosiding Pendidikan Dokter, 112–118.
Parag Jain, ravindra Pandey, S. S. S. (2015). Inflammation: Natural Resources and Its Applications.
Putra, M.P., Rahmah, S.B. & Kusmiati, M. (2015). Perbandingan Efektifitas Antipiretik antara Ekstrak Etanol Kunyit Putih (Curcuma zedoaria Rosc) dengan Parasetamol pada Tikus Model Demam’. Prosiding Pendidikan Dokter Universitas Islam Bandung, 2, 407–415.
Putra, M. P., Rahmah, S. B., & Kusmiati, M. (2015). Perbandingan Efektifitas Antipiretik antara Ekstrak Etanol Kunyit Putih (Curcuma zedoaria Rosc) dengan Parasetamol pada Tikus Model Demam. Prosiding Pendidikan Dokter Universitas Islam Bandung, 2, 407–415.
Ullah, H.M.A., et al. (2014). Evaluation of antinociceptive, in-vivo & in-vitro anti-inflammatory activity of ethanolic extract of Curcuma zedoaria rhizome’. BMC Complementary and Alternative Medicine, 14(1), 1–12.
Ullah, H. M. A., Zaman, S., Juhara, F., Akter, L., Tareq, S. M., Masum, E. H., & Bhattacharjee, R. (2014). Evaluation of antinociceptive, in-vivo & in-vitro anti-inflammatory activity of ethanolic extract of Curcuma zedoaria rhizome. BMC Complementary and Alternative Medicine, 14(1), 1–12. https://doi.org/10.1186/1472-6882-14-346
Utami, et. a. (2018). Uji Aktivitas Antiinflamasi Dan Toksisitas Infus. Kimia Khatulistiwa, 7(2), 107–112.
Yuda, P.E.S.K., Sasmita, G.A.P.Y. & Cahyaningsih, E. (2022). Aktivitas Anti-inflamasi Parem Instant Tradisional dari Bahan Usada Bali pada Mencit Inflamasi yang Diinduksi Karagenan. 20(2), 142–149.
Ayati, Z., Ramezani, M., Amiri, M. S., Moghadam, A. T., Rahimi, H., Abdollahzade, A., Sahebkar, A., & Emami, S. A. (2019). Ethnobotany, Phytochemistry and Traditional Uses of Curcuma spp. and Pharmacological Profile of Two Important Species (C. longa and C. zedoaria): A Review. Current Pharmaceutical Design, 25(8), 871–935. https://doi.org/10.2174/1381612825666190402163940
Gozali, K., Erny, T., Fiska, W. M., & Rico, S. A. (2022). Acute Toxicity of Extract of White Turmeric Rhizome (Curcuma Zedoaria) Review of Ld50 and Blood Cell Components. Jambura Journal of Health Sciences and Research, 4(3), 648–655. https://doi.org/10.35971/jjhsr.v4i3.13309
He, Y., et. a. (2015). Curcumin, inflammation, and chronic diseases: How are they linked? Molecules, 20(5), 9183–9213.
Hussain, T., et al. (2016). Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?’,. Oxidative Medicine and Cellular Longevity.
Jeong Ha, S., Song, K. M., Lee, J., Ho Kim, Y., Hyouck Lee, N., Eon Kim, Y., Lee, S., & Keun Jung, S. (2018). Preventive effect of Curcuma zedoaria extract on UVB-induced skin inflammation and photoaging. Journal of Food Biochemistry, 42(5), 1–11. https://doi.org/10.1111/jfbc.12598
Kim, K. M., Lee, J. Y., Jeon, B. H., Quan, K. T., Na, M., Nam, K. W., & Chae, S. (2021). Extract of curcuma zedoaria r. Prevents atherosclerosis in apolipoprotein e-deficient mice. Nutrition Research and Practice, 15(3), 319–328. https://doi.org/10.4162/nrp.2021.15.3.319
Lo, jia ye, Kamarudin, muhamad noor alfarizal, Hamdi, omer abdalla ahmed, Awang, K., & Kadir, habsah abdul. (2015). Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-?B activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells. https://doi.org/10.1039/c5fo00607d
Meltyza, E., et al. (2015). Perbandingan efek antiinflamasi ekstrak etanol kunyit putih (Curcuma zedoaria) dengan natrium diklorofenak pada tikus yang diinduksi dengan carrragenan’. Prosiding Pendidikan Dokter, 112–118.
Meltyza, E., Indriyanti, R. A., & Rahimah, S. B. (2015). Perbandingan efek antiinflamasi ekstrak etanol kunyit putih (Curcuma zedoaria) dengan natrium diklorofenak pada tikus yang diinduksi dengan carrragenan. Prosiding Pendidikan Dokter, 112–118.
Parag Jain, ravindra Pandey, S. S. S. (2015). Inflammation: Natural Resources and Its Applications.
Putra, M.P., Rahmah, S.B. & Kusmiati, M. (2015). Perbandingan Efektifitas Antipiretik antara Ekstrak Etanol Kunyit Putih (Curcuma zedoaria Rosc) dengan Parasetamol pada Tikus Model Demam’. Prosiding Pendidikan Dokter Universitas Islam Bandung, 2, 407–415.
Putra, M. P., Rahmah, S. B., & Kusmiati, M. (2015). Perbandingan Efektifitas Antipiretik antara Ekstrak Etanol Kunyit Putih (Curcuma zedoaria Rosc) dengan Parasetamol pada Tikus Model Demam. Prosiding Pendidikan Dokter Universitas Islam Bandung, 2, 407–415.
Ullah, H.M.A., et al. (2014). Evaluation of antinociceptive, in-vivo & in-vitro anti-inflammatory activity of ethanolic extract of Curcuma zedoaria rhizome’. BMC Complementary and Alternative Medicine, 14(1), 1–12.
Ullah, H. M. A., Zaman, S., Juhara, F., Akter, L., Tareq, S. M., Masum, E. H., & Bhattacharjee, R. (2014). Evaluation of antinociceptive, in-vivo & in-vitro anti-inflammatory activity of ethanolic extract of Curcuma zedoaria rhizome. BMC Complementary and Alternative Medicine, 14(1), 1–12. https://doi.org/10.1186/1472-6882-14-346
Utami, et. a. (2018). Uji Aktivitas Antiinflamasi Dan Toksisitas Infus. Kimia Khatulistiwa, 7(2), 107–112.
Yuda, P.E.S.K., Sasmita, G.A.P.Y. & Cahyaningsih, E. (2022). Aktivitas Anti-inflamasi Parem Instant Tradisional dari Bahan Usada Bali pada Mencit Inflamasi yang Diinduksi Karagenan. 20(2), 142–149.